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Inhibition of p38 MAPK reverses hypoxia-induced pulmonary artery endothelial dysfunction

Hypoxia-induced endothelial dysfunction plays a crucial role in the pathogenesis of hypoxic pulmonary hypertension. p38 MAPK expression is increased in the pulmonary artery following hypoxic exposure. Recent evidence suggests that increased p38 MAPK activity is associated with endothelial dysfunctio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Weerackody, Roshan P., Welsh, David J., Wadsworth, Roger M., Peacock, Andrew J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685327/
https://ncbi.nlm.nih.gov/pubmed/19201999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00977.2008
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