Epigallocatechin gallate inhibits angiotensin II-induced endothelial barrier dysfunction via inhibition of the p38 MAPK/HSP27 pathway

AIM: To investigate the effect of epigallocatechin gallate (EGCG) on angiotensin II (Ang II)-induced stress fiber formation and hyperpermeability in endothelial cells. METHODS: Human umbilical vein endothelial cells (HUVECs) were treated with Ang II in the absence or presence of EGCG or mitogen-acti...

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Main Authors: Yang, Dan, Liu, Jing, Tian, Cui, Zeng, Yong, Zheng, Yue-hong, Fang, Quan, Li, Hui-hua
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012900/
https://ncbi.nlm.nih.gov/pubmed/20644550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.75
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