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Heme induces rapid endothelial barrier dysfunction via the MKK3/p38MAPK axis
Several studies demonstrate that hemolysis and free heme in circulation cause endothelial barrier dysfunction and are associated with severe pathological conditions such as acute respiratory distress syndrome, acute chest syndrome, and sepsis. However, the precise molecular mechanisms involved in th...
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| Yayımlandı: | Blood |
|---|---|
| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society of Hematology
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7414589/ https://ncbi.nlm.nih.gov/pubmed/32548640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019003986 |
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