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Inhibition of Anaplerosis Attenuated Vascular Proliferation in Pulmonary Arterial Hypertension

Vascular remodeling is considered a key event in the pathogenesis of pulmonary arterial hypertension (PAH). However, mechanisms of gaining the proliferative phenotype by pulmonary vascular cells are still unresolved. Due to well-established pyruvate dehydrogenase (PDH) deficiency in PAH pathogenesis...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Valuparampil Varghese, Mathews, James, Joel, Eccles, Cody A, Niihori, Maki, Rafikova, Olga, Rafikov, Ruslan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7074087/
https://ncbi.nlm.nih.gov/pubmed/32041182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9020443
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