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The reversal of pulmonary vascular remodeling through inhibition of p38 MAPK-alpha: a potential novel anti-inflammatory strategy in pulmonary hypertension

The p38 mitogen-activated protein kinase (MAPK) system is increasingly recognized as an important inflammatory pathway in systemic vascular disease but its role in pulmonary vascular disease is unclear. Previous in vitro studies suggest p38 MAPKα is critical in the proliferation of pulmonary artery...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Church, Alistair C., Martin, Damien H., Wadsworth, Roger, Bryson, Gareth, Fisher, Andrew J., Welsh, David J., Peacock, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538235/
https://ncbi.nlm.nih.gov/pubmed/26024891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00038.2015
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