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Proofreading exonuclease activity of human DNA polymerase δ and its effects on lesion-bypass DNA synthesis
Replicative DNA polymerases possess 3′ → 5′ exonuclease activity to reduce misincorporation of incorrect nucleotides by proofreading during replication. To examine if this proofreading activity modulates DNA synthesis of damaged templates, we constructed a series of recombinant human DNA polymerase...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2685094/ https://ncbi.nlm.nih.gov/pubmed/19282447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp155 |
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