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Src-like adaptor protein (SLAP) is upregulated in antigen-stimulated mast cells and acts as a negative regulator

Our studies in the RBL-2H3 mast cell line suggest that responses to antigen (Ag) are negatively modulated through upregulation of Src-like adaptor protein (SLAP). Ag stimulation of RBL-2H3 cells leads to increased levels of SLAP (but not SLAP2) transcripts and protein over a period of several hours....

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Bibliographic Details
Main Authors: Park, Seung-Kiel, Qiao, Huihong, Beaven, Michael A.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684944/
https://ncbi.nlm.nih.gov/pubmed/19371953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2009.03.013
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