Knock-In Mouse Lines Expressing either Mitochondrial or Microsomal CYP1A1: Differing Responses to Dietary Benzo[a]pyrene as Proof of Principle

In the past, CYP1A1 protein was known to be located in the endoplasmic reticulum (ER; microsomes). More recently, CYP1A1 was shown also to be targeted to the inner mitochondrial membrane; mitochondrial import is dependent on NH(2)-terminal processing that exposes a cryptic targeting signal. It is in...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Dong, Hongbin, Dalton, Timothy P., Miller, Marian L., Chen, Ying, Uno, Shigeyuki, Shi, Zhanquan, Shertzer, Howard G., Bansal, Seema, Avadhani, Narayan G., Nebert, Daniel W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Pharmacology and Experimental Therapeutics 2009
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684908/
https://ncbi.nlm.nih.gov/pubmed/19047483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.051888
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados