Comparison of the 5′ nuclease activities of Taq DNA polymerase and its isolated nuclease domain

Many eubacterial DNA polymerases are bifunctional molecules having both polymerization (P) and 5′ nuclease (N) activities, which are contained in separable domains. We previously showed that the DNA polymerase I of Thermus aquaticus (TaqNP) endonucleolytically cleaves DNA substrates, releasing unpai...

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書誌詳細

出版年:	Proc Natl Acad Sci U S A
主要な著者:	Lyamichev, Victor, Brow, Mary Ann D., Varvel, Virgil E., Dahlberg, James E.
フォーマット:	Artigo
言語:	Inglês
出版事項:	National Academy of Sciences 1999
主題:	Biological Sciences
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26849/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10339555/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.11.6143
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