Comparison of the 5′ nuclease activities of Taq DNA polymerase and its isolated nuclease domain

Many eubacterial DNA polymerases are bifunctional molecules having both polymerization (P) and 5′ nuclease (N) activities, which are contained in separable domains. We previously showed that the DNA polymerase I of Thermus aquaticus (TaqNP) endonucleolytically cleaves DNA substrates, releasing unpai...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Lyamichev, Victor, Brow, Mary Ann D., Varvel, Virgil E., Dahlberg, James E.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1999
Materias:	Biological Sciences
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26849/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10339555/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.11.6143
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