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A cytosolic factor that inhibits K(ATP) channels expressed in Xenopus oocytes by impairing Mg-nucleotide activation by SUR1

ATP-sensitive K(+) (K(ATP)) channels couple cell metabolism to cell electrical activity. Wild-type (Kir6.2/SUR1) K(ATP) channels heterologously expressed in Xenopus oocytes give rise to very small inward currents in cell-attached patches. A large increase in the current is observed on patch excision...

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Detalhes bibliográficos
Main Authors: Tammaro, Paolo, Ashcroft, Frances M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683953/
https://ncbi.nlm.nih.gov/pubmed/19237428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.165126
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