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Mclk1(+/- )mice are not resistant to the development of atherosclerosis

BACKGROUND: Mice with a single copy of Mclk1 (a.k.a. Coq7), a gene that encodes a mitochondrial enzyme required for the biosynthesis of ubiquinone and other functions, live longer than wild-type mice. The prolonged survival implies a decreased mortality from age-dependent lethal pathologies. Atheros...

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Bibliografiske detaljer
Main Authors: Hughes, Bryan G, Hekimi, Siegfried
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683836/
https://ncbi.nlm.nih.gov/pubmed/19416523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-8-16
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