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Anti-Siglec-F antibody inhibits oral egg allergen induced intestinal eosinophilic inflammation in a mouse model
Siglec-F is a sialic acid binding immunoglobulin-superfamily receptor that is highly expressed on eosinophils. We have used a mouse model of oral egg ovalbumin (OVA)-induced eosinophilic inflammation of the gastrointestinal mucosa associated with diarrhea and weight loss to determine whether adminis...
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Hauptverfasser: | , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2009
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2683248/ https://ncbi.nlm.nih.gov/pubmed/19135419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2008.11.009 |
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