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Anti-Siglec-F antibody inhibits oral egg allergen induced intestinal eosinophilic inflammation in a mouse model

Siglec-F is a sialic acid binding immunoglobulin-superfamily receptor that is highly expressed on eosinophils. We have used a mouse model of oral egg ovalbumin (OVA)-induced eosinophilic inflammation of the gastrointestinal mucosa associated with diarrhea and weight loss to determine whether adminis...

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Detalhes bibliográficos
Main Authors: Song, Dae Jin, Cho, Jae Youn, Miller, Marina, Strangman, Wendy, Zhang, Mai, Varki, Ajit, Broide, David H
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683248/
https://ncbi.nlm.nih.gov/pubmed/19135419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2008.11.009
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