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Promiscuous Usage of Nucleotides by the DNA Helicase of Bacteriophage T7: DETERMINANTS OF NUCLEOTIDE SPECIFICITY

The multifunctional protein encoded by gene 4 of bacteriophage T7 (gp4) provides both helicase and primase activity at the replication fork. T7 DNA helicase preferentially utilizes dTTP to unwind duplex DNA in vitro but also hydrolyzes other nucleotides, some of which do not support helicase activit...

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Bibliografski detalji
Glavni autori: Satapathy, Ajit K., Crampton, Donald J., Beauchamp, Benjamin B., Richardson, Charles C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682877/
https://ncbi.nlm.nih.gov/pubmed/19297330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M900557200
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