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Novel Glutaredoxin Activity of the Yeast Prion Protein Ure2 Reveals a Native-like Dimer within Fibrils

Ure2 is the protein determinant of the Saccharomyces cerevisiae prion [URE3]. Ure2 has structural similarity to glutathione transferases, protects cells against heavy metal and oxidant toxicity in vivo, and shows glutathione-dependent peroxidase activity in vitro. Here we report that Ure2 (which has...

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Detalhes bibliográficos
Main Authors: Zhang, Zai-Rong, Perrett, Sarah
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682854/
https://ncbi.nlm.nih.gov/pubmed/19321443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M901189200
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