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Acetylation of Nrf2 by p300/CBP Augments Promoter-Specific DNA Binding of Nrf2 during the Antioxidant Response

To maintain intracellular redox homeostasis, genes encoding many antioxidants and detoxification enzymes are transcriptionally upregulated upon deleterious oxidative stress through the cis antioxidant responsive elements (AREs) in their promoter regions. Nrf2 is the critical transcription factor res...

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Detalhes bibliográficos
Main Authors: Sun, Zheng, Chin, Y. Eugene, Zhang, Donna D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682049/
https://ncbi.nlm.nih.gov/pubmed/19273602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01639-08
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