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Acetylation of Nrf2 by p300/CBP Augments Promoter-Specific DNA Binding of Nrf2 during the Antioxidant Response
To maintain intracellular redox homeostasis, genes encoding many antioxidants and detoxification enzymes are transcriptionally upregulated upon deleterious oxidative stress through the cis antioxidant responsive elements (AREs) in their promoter regions. Nrf2 is the critical transcription factor res...
Αποθηκεύτηκε σε:
Κύριοι συγγραφείς: | , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
American Society for Microbiology (ASM)
2009
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2682049/ https://ncbi.nlm.nih.gov/pubmed/19273602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01639-08 |
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