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Effects of thapsigargin and phenylephrine on calcineurin and protein kinase C signaling functions in cardiac myocytes
Neonatal rat cardiac myocytes were exposed to 10 nM thapsigargin (TG) or 20 μM phenylephrine (PE) to compare resulting alterations of Ca(2+) homeostasis. Either treatment results in resting cytosolic [Ca(2+)] rise and reduction of Ca(2+) signals in myocytes following electrical stimuli. In fact, ATP...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2681384/ https://ncbi.nlm.nih.gov/pubmed/19244478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00594.2008 |
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