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Silencing calcineurin A subunit reduces SERCA2 expression in cardiac myocytes
Resting intracellular Ca(2+) can be raised, in neonatal rat cardiac myocytes, by exposure to very low concentration of thapsigargin (TG). Such a Ca(2+) rise yields calcineurin (CN) activation demonstrated by increased expression of transfected luciferase cDNA under control of nuclear factor of activ...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3023267/ https://ncbi.nlm.nih.gov/pubmed/21057045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00841.2010 |
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