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Effects of thapsigargin and phenylephrine on calcineurin and protein kinase C signaling functions in cardiac myocytes

Neonatal rat cardiac myocytes were exposed to 10 nM thapsigargin (TG) or 20 μM phenylephrine (PE) to compare resulting alterations of Ca(2+) homeostasis. Either treatment results in resting cytosolic [Ca(2+)] rise and reduction of Ca(2+) signals in myocytes following electrical stimuli. In fact, ATP...

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Bibliografiske detaljer
Main Authors: Prasad, Anand Mohan, Inesi, Giuseppe
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681384/
https://ncbi.nlm.nih.gov/pubmed/19244478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00594.2008
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