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Th2 cytokine-induced upregulation of 11β-hydroxysteroid dehydrogenase-1 facilitates glucocorticoid suppression of proasthmatic airway smooth muscle function

The anti-inflammatory actions of endogenous glucocorticoids (GCs) are regulated by the activities of the GC-activating and -inactivating enzymes, 11β-hydroxysteroid dehydrogenase (11β-HSD)-1 and 11β-HSD2, respectively, that catalyze the interconversion of the inert GC, cortisone, and its bioactive d...

詳細記述

保存先:
書誌詳細
主要な著者: Hu, Aihua, Fatma, Sumbul, Cao, Jing, Grunstein, Judith S., Nino, Gustavo, Grumbach, Yael, Grunstein, Michael M.
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681349/
https://ncbi.nlm.nih.gov/pubmed/19251840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90572.2008
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