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Intracellular Zn(2+) increases contribute to the progression of excitotoxic Ca(2+) increases in apical dendrites of CA1 pyramidal neurons

Sustained intracellular Ca(2+) elevation is a well-established contributor to neuronal injury following excessive activation of NMDA-type glutamate receptors. Zn(2+) can also be involved in excitotoxic degeneration, but the relative contributions of these two cations to the initiation and progressio...

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Autors principals: Vander Jagt, T.A., Connor, J.A., Weiss, J.H., Shuttleworth, C.W.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680677/
https://ncbi.nlm.nih.gov/pubmed/19135505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2008.11.052
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