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Emergence of a spermine-sensitive, non-inactivating conductance in mature hippocampal CA1 pyramidal neurons upon reduction of extracellular Ca(2+): dependence on intracellular Mg(2+) and ATP.

Large and protracted elevations of intracellular [Ca(2+)] and [Na(+)] play a crucial role in neuronal injury in ischemic conditions. In addition to excessive glutamate receptor activation, other ion channels may contribute to disruption of intracellular ionic homeostasis. During episodes of ischemia...

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Detalhes bibliográficos
Main Authors: Chinopoulos, Christos, Connor, John A, Shuttleworth, C William
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853290/
https://ncbi.nlm.nih.gov/pubmed/16962211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2006.07.013
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