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Effect of phenytoin on sodium conductances in rat hippocampal CA1 pyramidal neurons

The antiepileptic drug phenytoin (PHT) is thought to reduce the excitability of neural tissue by stabilizing sodium channels (Na(V)) in inactivated states. It has been suggested the fast-inactivated state (I(F)) is the main target, although slow inactivation (I(S)) has also been implicated. Other st...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Neurophysiol
Egile Nagusiak: Zeng, Zhen, Hill-Yardin, Elisa L., Williams, David, O'Brien, Terence, Serelis, Andris, French, Christopher R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5144711/
https://ncbi.nlm.nih.gov/pubmed/27489371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.01060.2015
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