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Effect of phenytoin on sodium conductances in rat hippocampal CA1 pyramidal neurons
The antiepileptic drug phenytoin (PHT) is thought to reduce the excitability of neural tissue by stabilizing sodium channels (Na(V)) in inactivated states. It has been suggested the fast-inactivated state (I(F)) is the main target, although slow inactivation (I(S)) has also been implicated. Other st...
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| Опубликовано в: : | J Neurophysiol |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Physiological Society
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5144711/ https://ncbi.nlm.nih.gov/pubmed/27489371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.01060.2015 |
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