Effect of phenytoin on sodium conductances in rat hippocampal CA1 pyramidal neurons

The antiepileptic drug phenytoin (PHT) is thought to reduce the excitability of neural tissue by stabilizing sodium channels (Na(V)) in inactivated states. It has been suggested the fast-inactivated state (I(F)) is the main target, although slow inactivation (I(S)) has also been implicated. Other st...

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Detaylı Bibliyografya
Yayımlandı:J Neurophysiol
Asıl Yazarlar: Zeng, Zhen, Hill-Yardin, Elisa L., Williams, David, O'Brien, Terence, Serelis, Andris, French, Christopher R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2016
Konular:
Cellular and Molecular Properties of Neurons
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5144711/
https://ncbi.nlm.nih.gov/pubmed/27489371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.01060.2015
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