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Protection of Vascular Barrier Integrity by Activated Protein C in Murine Models Depends on Protease-Activated Receptor-1
Protease activated receptor-1 (PAR1) mediates barrier protective signaling of activated protein C (APC) in human endothelial cells in vitro and may contribute to APC’s beneficial effects in patients with severe sepsis. Mouse models are of key importance for translational research but species differe...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2680237/ https://ncbi.nlm.nih.gov/pubmed/19350118 |
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