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Protease Activated Receptor-1 Cleaved at R46 Mediates Cytoprotective Effects
BACKGROUND: Activated protein C (aPC) mediates powerful cytoprotective effects through protease activated receptor (PAR)-1 that translate into reduced harm in mouse injury models. However, it remains elusive how aPC-activated PAR1 can mediate cytoprotective effects while thrombin activation does the...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3419798/ https://ncbi.nlm.nih.gov/pubmed/22712885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2012.04825.x |
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