Apc inhibition of Wnt signaling regulates supernumerary tooth formation during embryogenesis and throughout adulthood

The ablation of Apc function or the constitutive activation of β-catenin in embryonic mouse oral epithelium results in supernumerary tooth formation, but the underlying mechanisms and whether adult tissues retain this potential are unknown. Here we show that supernumerary teeth can form from multipl...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wang, Xiu-Ping, O'Connell, Daniel J., Lund, Jennifer J., Saadi, Irfan, Kuraguchi, Mari, Turbe-Doan, Annick, Cavallesco, Resy, Kim, Hyunsoo, Park, Peter J., Harada, Hidemitsu, Kucherlapati, Raju, Maas, Richard L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Company of Biologists 2009
Gaiak:
Development and Disease
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680115/
https://ncbi.nlm.nih.gov/pubmed/19429790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.033803
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