ATP ground- and transition-states of bacterial enhancer binding AAA+ ATPases support complex formation with their target protein, σ54.

Transcription initiation by the σ54-form of bacterial RNA polymerase requires hydrolysis of ATP by an enhancer binding protein (EBP). We present SAS-based solution structures of the ATPase domain of the EBP NtrC1 from Aquifex aeolicus in different nucleotide states. Structures of apo protein and tha...

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Main Authors: Chen, Baoyu, Doucleff, Michaeleen, Wemmer, David E., De Carlo, Sacha, Huang, Hector H., Nogales, Eva, Hoover, Timothy R., Kondrashkina, Elena, Guo, Liang, Nixon, B. Tracy
格式: Artigo
語言:Inglês
出版: 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680074/
https://ncbi.nlm.nih.gov/pubmed/17437715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2007.02.007
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