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Nucleotide-induced asymmetry within ATPase activator ring drives σ54–RNAP interaction and ATP hydrolysis

It is largely unknown how the typical homomeric ring geometry of ATPases associated with various cellular activities enables them to perform mechanical work. Small-angle solution X-ray scattering, crystallography, and electron microscopy (EM) reconstructions revealed that partial ATP occupancy cause...

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Detalhes bibliográficos
Main Authors: Sysoeva, Tatyana A., Chowdhury, Saikat, Guo, Liang, Nixon, B. Tracy
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3841738/
https://ncbi.nlm.nih.gov/pubmed/24240239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.229385.113
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