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Structure of the RNA-Polymerase Core Binding Domain of σ(54) Reveals a Likely Conformational Fracture Point

Transcription initiation by bacterial σ(54)-RNA polymerase requires a conformational change of the holopolymerase-DNA complex, driven by an enhancer binding protein. Although structures of the core polymerase and the more common σ(70) factor have been determined, little is known about the structure...

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Detalhes bibliográficos
Main Authors: Hong, Eunmi, Doucleff, Michaeleen, Wemmer, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195411/
https://ncbi.nlm.nih.gov/pubmed/19426742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.04.070
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