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Structural Basis of DNA Recognition by the Alternative Sigma-Factor, σ54

The σ subunit of bacterial RNA polymerase (RNAP) regulates gene expression by directing RNAP to specific promoters. Unlike σ(70)-type proteins, the alternative σ factor, σ(54), requires interaction with an ATPase to open DNA. We present the solution structure of the C-terminal domain of σ(54) bound...

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Detalhes bibliográficos
Main Authors: Doucleff, Michaeleen, Pelton, Jeffrey G., Lee, Peter S., Nixon, B. Tracy, Wemmer, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680387/
https://ncbi.nlm.nih.gov/pubmed/17481658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.04.019
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