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Myocardial Overexpression of Mecr, a Gene of Mitochondrial FAS II Leads to Cardiac Dysfunction in Mouse

It has been recently recognized that mammalian mitochondria contain most, if not all, of the components of fatty acid synthesis type II (FAS II). Among the components identified is 2-enoyl thioester reductase/mitochondrial enoyl-CoA reductase (Etr1/Mecr), which catalyzes the NADPH-dependent reductio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Zhijun, Leskinen, Hanna, Liimatta, Erkki, Sormunen, Raija T., Miinalainen, Ilkka J., Hassinen, Ilmo E., Hiltunen, J. Kalervo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680037/
https://ncbi.nlm.nih.gov/pubmed/19440339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005589
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