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Endostatin Overexpression Specifically in the Lens and Skin Leads to Cataract and Ultrastructural Alterations in Basement Membranes

Endostatin, a proteolytic fragment of type XVIII collagen, has been shown to inhibit angiogenesis, tumor growth, and endothelial cell proliferation and migration. We analyzed its functions in vivo by generating transgenic mice in which it was overexpressed in the skin and lens capsule under the kera...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Elamaa, Harri, Sormunen, Raija, Rehn, Marko, Soininen, Raija, Pihlajaniemi, Taina
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Investigative Pathology 2005
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602290/
https://ncbi.nlm.nih.gov/pubmed/15632014
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