Mitochondrial Dysfunction Due to Lack of Manganese Superoxide Dismutase Promotes Hepatocarcinogenesis

Aims: One of the cancer hallmarks is mitochondrial dysfunction associated with oxidative stress. Among the first line of defense against oxidative stress is the dismutation of superoxide radicals, which in the mitochondria is carried out by manganese superoxide dismutase (MnSOD). Accordingly, carcin...

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Vydáno v:Antioxid Redox Signal
Hlavní autoři: Konzack, Anja, Jakupovic, Mirza, Kubaichuk, Kateryna, Görlach, Agnes, Dombrowski, Frank, Miinalainen, Ilkka, Sormunen, Raija, Kietzmann, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2015
Témata:
Forum Original Research CommunicationsRedox Medicine (H. H.H.W. Schmidt and F. Di Lisa, Eds.)
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657515/
https://ncbi.nlm.nih.gov/pubmed/26422659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2015.6318
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