Mitochondrial Dysfunction Due to Lack of Manganese Superoxide Dismutase Promotes Hepatocarcinogenesis

Aims: One of the cancer hallmarks is mitochondrial dysfunction associated with oxidative stress. Among the first line of defense against oxidative stress is the dismutation of superoxide radicals, which in the mitochondria is carried out by manganese superoxide dismutase (MnSOD). Accordingly, carcin...

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Detalhes bibliográficos
Publicado no:Antioxid Redox Signal
Main Authors: Konzack, Anja, Jakupovic, Mirza, Kubaichuk, Kateryna, Görlach, Agnes, Dombrowski, Frank, Miinalainen, Ilkka, Sormunen, Raija, Kietzmann, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Forum Original Research CommunicationsRedox Medicine (H. H.H.W. Schmidt and F. Di Lisa, Eds.)
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657515/
https://ncbi.nlm.nih.gov/pubmed/26422659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2015.6318
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