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Preferential Zn(2+) influx through Ca(2+)-permeable AMPA/kainate channels triggers prolonged mitochondrial superoxide production
Synaptically released Zn(2+) can enter and cause injury to postsynaptic neurons. Microfluorimetric studies using the Zn(2+)-sensitive probe, Newport green, examined levels of [Zn(2+)](i) attained in cultured cortical neurons on exposure to N-methyl-d-asparte, kainate, or high K(+) (to activate volta...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The National Academy of Sciences
1999
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC26798/ https://ncbi.nlm.nih.gov/pubmed/10051656 |
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