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Rapid Ca(2+) Entry through Ca(2+)-Permeable AMPA/Kainate Channels Triggers Marked Intracellular Ca(2+)Rises and Consequent Oxygen Radical Production

The widespread neuronal injury that results after brief activation of highly Ca(2+)-permeable NMDA channels may, in large part, reflect mitochondrial Ca(2+) overload and the consequent production of injurious oxygen radicals. In contrast, AMPA/kainate receptor activation generally causes slower toxi...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Carriedo, Sean G., Yin, Hong Zhen, Sensi, Stefano L., Weiss, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6793031/
https://ncbi.nlm.nih.gov/pubmed/9742143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-19-07727.1998
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