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Ca(2+)-Permeable AMPA/Kainate and NMDA Channels: High Rate of Ca(2+) Influx Underlies Potent Induction of Injury

Neurodegeneration may occur secondary to glutamate-triggered Ca(2+) influx through any of three routes: NMDA channels, voltage-sensitive Ca(2+) channels (VSCC), and Ca(2+)-permeable AMPA/kainate channels (Ca-A/K). This study aims to examine Ca(2+) ion dynamics in the generation of excitotoxic injury...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Lu, You Ming, Yin, Hong Zhen, Chiang, Juna, Weiss, John H.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 1996
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6578887/
https://ncbi.nlm.nih.gov/pubmed/8757258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.16-17-05457.1996
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