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Prevention of upper aerodigestive tract cancer in zinc-deficient rodents: Inefficacy of genetic or pharmacological disruption of COX-2

Zinc deficiency in humans is associated with an increased risk of upper aerodigestive tract (UADT) cancer. In rodents, zinc deficiency predisposes to carcinogenesis by causing proliferation and alterations in gene expression. We examined whether in zinc-deficient rodents, targeted disruption of the...

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Detalhes bibliográficos
Main Authors: Fong, Louise Y.Y., Jiang, Yubao, Riley, Maurisa, Liu, Xianglan, Smalley, Karl J., Guttridge, Denis C., Farber, John L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679643/
https://ncbi.nlm.nih.gov/pubmed/17985342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.23221
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