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Targeted expression of ornithine decarboxylase antizyme prevents upper aerodigestive tract carcinogenesis in p53-deficient mice

Upper aerodigestive tract (UADT) cancers of the oral cavity and esophagus are a significant global health burden, and there is an urgent need to develop relevant animal models to identify chemopreventive and therapeutic strategies to combat these diseases. Antizyme (AZ) is a multifunctional negative...

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Détails bibliographiques
Auteurs principaux: Feith, David J., Pegg, Anthony E., Fong, Louise Y.Y.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581602/
https://ncbi.nlm.nih.gov/pubmed/23222816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgs377
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