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Cyclooxygenase-2 Expression is an Independent Predictor of Poor Prognosis in Colon Cancer

PURPOSE: Cyclooxygenase-2 (COX-2, PTGS2) is considered to play an important role in colorectal carcinogenesis, and is often upregulated in colon cancers. However, previous data on the influence of COX-2 expression on patient outcome have been conflicting. EXPERIMENTAL DESIGN: Utilizing 662 colon can...

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Détails bibliographiques
Auteurs principaux: Ogino, Shuji, Kirkner, Gregory J., Nosho, Katsuhiko, Irahara, Natsumi, Kure, Shoko, Shima, Kaori, Hazra, Aditi, Chan, Andrew T., Dehari, Reiko, Giovannucci, Edward L., Fuchs, Charles S.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679582/
https://ncbi.nlm.nih.gov/pubmed/19088039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-1841
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