A Cohort Study of Cyclin D1Expression and Prognosis in 602 Colon Cancer Cases

PURPOSE: Cyclin D1 and cyclin-dependent kinases (CDK) are commonly activated in colorectal cancer. The activity of cyclin D1 can be blocked by CDK inhibitors, including p27 (CDKN1B) and p21 (CDKN1A, which is induced by p53). However, prognostic significance of tumoral cyclin D1 remains uncertain, an...

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Bibliografiset tiedot
Päätekijät: Ogino, Shuji, Nosho, Katsuhiko, Irahara, Natsumi, Kure, Shoko, Shima, Kaori, Baba, Yoshifumi, Toyoda, Saori, Chen, Li, Giovannucci, Edward L., Meyerhardt, Jeffrey A., Fuchs, Charles S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921858/
https://ncbi.nlm.nih.gov/pubmed/19549773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-3330
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