Matrix Metalloproteinase-2-deficient Fibroblasts Exhibit an Alteration in the Fibrotic Response to Connective Tissue Growth Factor/CCN2 because of an Increase in the Levels of Endogenous Fibronectin

Matrix metalloproteinase-2 (MMP-2) is an important extracellular matrix remodeling enzyme, and it has been involved in different fibrotic disorders. The connective tissue growth factor (CTGF/CCN2), which is increased in these pathologies, induces the production of extracellular matrix proteins. To u...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Droppelmann, Cristian A., Gutiérrez, Jaime, Vial, Cecilia, Brandan, Enrique
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Biochemistry and Molecular Biology 2009
Θέματα:
Glycobiology and Extracellular Matrices
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679456/
https://ncbi.nlm.nih.gov/pubmed/19276073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807352200
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