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Decorin Interacts with Connective Tissue Growth Factor (CTGF)/CCN2 by LRR12 Inhibiting Its Biological Activity

Fibrotic disorders are the end point of many chronic diseases in different tissues, where an accumulation of the extracellular matrix occurs, mainly because of the action of the connective tissue growth factor (CTGF/CCN2). Little is known about how this growth factor activity is regulated. We found...

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Bibliografiska uppgifter
Huvudupphovsmän: Vial, Cecilia, Gutiérrez, Jaime, Santander, Cristian, Cabrera, Daniel, Brandan, Enrique
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129205/
https://ncbi.nlm.nih.gov/pubmed/21454550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.189365
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