Identification of Loss of Function Mutations in Human Genes Encoding RIG-I and MDA5: IMPLICATIONS FOR RESISTANCE TO TYPE I DIABETES

Retinoic acid-inducible gene I (RIG-I) and melanoma differentiation-associated gene 5 (MDA5) are essential for detecting viral RNA and triggering antiviral responses, including production of type I interferon. We analyzed the phenotype of non-synonymous mutants of human RIG-I and MDA5 reported in da...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Shigemoto, Taeko, Kageyama, Maiko, Hirai, Reiko, Zheng, JiPing, Yoneyama, Mitsutoshi, Fujita, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679434/
https://ncbi.nlm.nih.gov/pubmed/19324880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809449200
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados