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Characterization of a novel anti-human TNF-α murine monoclonal antibody with high binding affinity and neutralizing activity
In order to develop an anti-human TNF-α mAb, mice were immunized with recombinant human TNF-α. A murine mAb, TSK114, which showed the highest binding activity for human TNF-α was selected and characterized. TSK114 specifically bound to human TNF-α without cross-reactivity with the homologous murine...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Korean Society of Medical Biochemistry and Molecular Biology
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2679312/ https://ncbi.nlm.nih.gov/pubmed/18305396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2008.40.1.35 |
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