Conformation-Dependent High-Affinity Potent Ricin-Neutralizing Monoclonal Antibodies

Ricin is a potential biothreat agent with no approved antidote available for ricin poisoning. The aim of this study was to develop potent antibody-based antiricin antidotes. Four strong ricin resistant hybridoma clones secreting antiricin monoclonal antibodies (mAbs) were developed. All four mAbs ar...

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Autori principali: Hu, Wei-Gang, Yin, Junfei, Chau, Damon, Hu, Charles Chen, Lillico, Dustin, Yu, Justin, Negrych, Laurel M., Cherwonogrodzky, John W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591125/
https://ncbi.nlm.nih.gov/pubmed/23484120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/471346
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