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IL-12Rβ2 Promotes the Development of CD4(+)CD25(+) Regulatory T Cells

We have previously shown that mice lacking the IL-12-specific receptor subunit β2 (IL-12Rβ2) develop more severe experimental autoimmune encephalomyelitis than wild-type (WT) mice. The mechanism underlying this phenomenon is not known; nor is it known whether deficiency of IL-12Rβ2 impacts other aut...

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Autors principals: Zhao, Zhao, Yu, Shuo, Fitzgerald, Denise C., Elbehi, Mohamed, Ciric, Bogoljub, Rostami, A. M., Zhang, Guang-Xian
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679170/
https://ncbi.nlm.nih.gov/pubmed/18768841
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