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Interferon γ expressed by a recombinant respiratory syncytial virus attenuates virus replication in mice without compromising immunogenicity

Interferon γ (IFN-γ) has pleiotropic biological effects, including intrinsic antiviral activity as well as stimulation and regulation of immune responses. An infectious recombinant human respiratory syncytial virus (rRSV/mIFN-γ) was constructed that encodes murine (m) IFN-γ as a separate gene insert...

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Detaylı Bibliyografya
Asıl Yazarlar: Bukreyev, Alexander, Whitehead, Stephen S., Bukreyeva, Natalya, Murphy, Brian R., Collins, Peter L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 1999
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC26790/
https://ncbi.nlm.nih.gov/pubmed/10051648
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